Regan Memmot

Regan Memmot

Company: The Ohio State University

Job title: Assistant Professor in Medical Oncology


Join me at Wnt


Inhibiting β-Catenin to Target “Drug-Tolerant Persister Cells” in Metastatic EGFR-Mutant Non-Small Cell Lung Cancer 10:40 am

• Detailing how stabilization of β-catenin by EGFR TKIs (tyrosine kinase inhibitors) enriches for cancer cells with stem-like properties • Demonstrating that EGFR TKIs increase the stability of β-catenin through a novel mechanism that is dependent on Notch3 • Providing combinational work for a β-catenin inhibitor with an EGFR TKI causes a deeper level of…Read more

day: Day Two

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